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Epigenetic clocks: evidence and limitations

Horvath’s 2013 paper describes DNA methylation age estimation across tissues and cell types. That method is not evidence of a validated UAE exposome test or of the efficacy of an anti-ageing product. Population, tissue, validation and the intended use of a model remain important.

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What is an epigenetic clock?

An epigenetic clock is a statistical model using DNA methylation patterns to estimate age-related variation. It is not a complete exposure history, a diagnosis or proof that a product reverses ageing.

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What is an epigenetic clock?

An epigenetic clock is a statistical model using DNA methylation patterns to estimate age-related variation. It is not a complete exposure history, a diagnosis or proof that a product reverses ageing.

Research context, not medical advice or an independently reviewed clinical recommendation.

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